Our research is focused on pharmacokinetic/pharmacodynamic interactions of antibiotics using static and kinetic time-kill experiments to evaluate the antibacterial effects in terms of killing and emergence of resistance. In recent years we have focused on exploring the potential of antibiotic combinations in the treatment of multidrug-resistant Gram-negative bacteria and also new methods for efficient screening of synergistic interactions and rapid determination of antibiotic susceptibilities.

Our primary objective is to generate in vitro data that are clinically relevant and can be used to guide the choice of appropriate drugs and dosing regimens for patients infected with multidrug-resistant bacteria.


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The Antibiotic research unit,

Department of Medical Sciences

Uppsala University Hospital

Clinical microbiology, Hubben, 5th floor

S-751 85  Uppsala


Visiting Address

The Antibiotic research unit

Hubben, 5th floor

Dag Hammarskjölds v. 38

752 37 Uppsala



Pernilla Lagerbäck: +46(0)18 611 34 80